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Updated: Jun 7, 2026

Three-dimensional Biomimetic Technology: Novel Biorubber Creates Defined Micro- and Macro-scale Architectures in Collagen Hydrogels
Published on: February 12, 2016
Three-dimensional biomimetic mineralization of dense hydrogel templates
Gao Liu1, Dacheng Zhao, Antoni P Tomsia
1Environmental Energy Technologies Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
Abstract:
An electric-current-assisted method was used to mineralize dense hydrogels and create hydroxyapatite/hydrogel composites with unique hierarchical structures. The microstructure of the final material can be controlled by the mineralization technique and the chemistry of the organic matrix. A hydroxyapatite/hydrogel composite was obtained with a large inorganic content (approximately 60% of the weight of the organics). After being heated to 1050 degrees C, the sintered inorganic phase has a very uniformly distributed porosity and its Brunauer-Emmett-Teller (BET) surface area is 0.68 m(2)/g.
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