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Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation
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Modulating T-cell homeostasis with IL-7: preclinical and clinical studies

C M Capitini1, A A Chisti, C L Mackall

  • 1Immunology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. capitinic@mail.nih.gov

Journal of Internal Medicine
|July 23, 2009
PubMed
Summary

Interleukin-7 (IL-7) is vital for T cell development and survival, impacting immune homeostasis. This review explores IL-7 biology and its clinical applications in disease, including IL-7 blockade strategies.

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