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Published on: July 5, 2017
[Flavonoids from roots of Flemingia philippinensis]
Hua Li1, Meihua Yang, Xiaojun Ma
1Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China. lixian78101@163.com
Objective:
To investigate the chemical constituents of the roots of Flemingia philippinensis.
Method:
Silica gel, ODS silica gel and Sephadex LH-20 column chromatography were employed for the isolation and purification. The structures were identified on the basis of spectral data (MS, 1H-NMR and 13C-NMR) and chemical evidence.
Result:
Seven compounds were isolated from the 75% ethanolic extract of the roots of F. philippinensis and identified as follows: flemiphilippinin D (1), dorsmanins I (2), osajin (3), eriosematin (4), lupinalbin A (5), genistein (6) and 3'-O-methylorobol (7).
Conclusion:
The compounds 2, 3 and 4 were isolated from the genus Flemingia for the first time. The compounds 2 and 4 were obtained from the Flemingia philippinensis for the first time.
