Scar classification in cutaneous lupus erythematosus: morphological description

Area of Science:

• Dermatology
• Pathology

Background:

• Scarring is a primary cause of disability in discoid lupus erythematosus (DLE).
• No prior studies have classified DLE-associated scar types.
• This research addresses the lack of scar classification in DLE.

Purpose of the Study:

• To classify DLE scars based on their morphological characteristics.
• To establish a standardized classification system for DLE scars.

Main Methods:

• Histologically confirmed DLE patients (n=45) were included.
• Scars were assessed and scored based on anatomical localization.
• Morphological subtypes were identified within each anatomical scar type.

Main Results:

• Six main morphological scar types were identified in DLE patients.
• Scars were prevalent, affecting scalp, hairy areas, non-hairy areas, mucosa, and nails.
• DLE scars can manifest as textural and pigmentary changes.

Conclusions:

• A classification system for DLE scars was developed.
• Early identification and classification of DLE scars may inform treatment decisions.
• Tailoring therapies to specific scar types could improve patient outcomes.