Related Experiment Video
Updated: Jun 21, 2026

07:34
A Cost-effective and Reliable Method to Predict Mechanical Stress in Single-use and Standard Pumps
Published on: August 5, 2015
Regional anaesthesia elastomeric pump performance after a single use and subsequent refill: a laboratory study.
1Ninewells Hospital and Medical School, Dundee, UK.
Anaesthesia
|July 24, 2009
Summary
Refilling elastomeric pumps for regional anesthesia is cost-effective. These devices maintain satisfactory flow rates after a single refill, offering a viable alternative to costly single-use pumps.
Area of Science:
- Anesthesiology
- Biomedical Engineering
Background:
- Ambulatory local anesthetic delivery systems often have limited infusion durations.
- Replacing pumps incurs significant costs ($300-500) for consumables.
Purpose of the Study:
- To evaluate the flow delivery performance of refilled elastomeric infusion pumps.
- To determine if refilled pumps maintain satisfactory performance for regional anesthesia.
Main Methods:
- 31 elastomeric pumps with specific flow capabilities were used clinically, refilled, and tested in a laboratory setting.
- Flow delivery was assessed for the second infusion cycle.
Main Results:
- Initial over-infusion (<10 ml/h) was observed in the first hour of the second infusion.
- All pumps stabilized, with performance within 150% of predicted rates by the second hour.
- Subsequent performance remained within safe limits and manufacturer specifications for primary infusion.
Conclusions:
- Refilled elastomeric regional anesthesia pumps demonstrate satisfactory performance after a single reuse.
- This approach offers a cost-effective solution for prolonging nerve blockade compared to single-use pumps.
Related Concept Videos
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
One of the advantages of...
Local Anesthetics: Pharmacokinetics
The potency and duration of action of local anesthetics (LAs) are determined by their pharmacokinetics. Pharmacokinetics describes how LAs are absorbed, distributed, metabolized, and eliminated from the body. When administered to the vascular tissues, LAs are quickly absorbed and enter the systemic circulation, reducing their localized effects. Adding vasoconstrictors such as epinephrine to LAs reduces their absorption into the systemic circulation, making them clinically effective. The...
Local Anesthetics: Clinical Application as Epidural Anesthesia
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
