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Updated: Jun 21, 2026

Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites
Published on: May 18, 2016
Subcutaneous nodules with sporotrichoid spread
Mark N Schwendiman1, Ryan P Johnson, J Scott Henning
1Des Moines University College of Osteopathic Medicine and Surgery, Des Moines, Iowa, USA.
Mycobacterium marinum infections, often from aquariums, cause skin nodules. Prompt diagnosis and minocycline treatment led to healing in a rose gardener with this atypical mycobacterial infection.
Area of Science:
- Infectious Diseases
- Dermatology
- Microbiology
Background:
- Mycobacterium marinum is an emerging pathogen globally.
- Aquariums and swimming pools are common sources of M. marinum.
- Infections typically manifest as subcutaneous nodules and lymphangitis.
Observation:
- A 61-year-old female presented with a two-month history of subcutaneous nodules.
- The patient reported recent activities including rose gardening and aquarium cleaning.
- Histological and tissue culture analysis confirmed M. marinum infection.
Findings:
- The patient was successfully treated with minocycline.
- Treatment resulted in the eventual healing of nodules.
- No new lesions recurred following the initiation of therapy.
Implications:
- Mycobacterium marinum should be considered in cases of ascending nodules along lymphatic pathways.
- Early diagnosis and appropriate antibiotic treatment are crucial for favorable outcomes.
- Awareness of environmental exposures aids in identifying potential M. marinum infections.
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