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Unknown: bilateral symmetrical papules on the eyelid
Ana F Duarte1, Ana Nogueira, Carmen Lisboa
1Department of Dermatology and Venereology, Hospital de São João, Porto, Portugal. duarte.af.t30@gmail.com
Dermatology Online Journal
|July 24, 2009
Summary
Clear cell syringoma, a rare eyelid tumor, can mimic xanthelasma. This case highlights diagnosis via biopsy and successful treatment with CO2 laser and surgery, with no recurrence.
Area of Science:
- Dermatology
- Ophthalmology
- Pathology
Background:
- Eyelid lesions present diagnostic challenges.
- Xanthelasma is a common differential diagnosis for eyelid papules.
Purpose of the Study:
- To report a case of clear cell syringoma presenting as eyelid papules.
- To discuss diagnostic and treatment strategies for this rare condition.
Main Methods:
- Clinical presentation of a 46-year-old woman with 5-year history of yellowish, symmetric, progressive eyelid papules.
- Skin biopsy for histopathological examination.
- Treatment with CO2 laser and surgical excision.
Main Results:
- Histopathology confirmed clear cell syringoma, a rare variant.
- Successful treatment with CO2 laser and surgical excision.
- No recurrence observed at 6-month follow-up.
Conclusions:
- Clear cell syringoma should be considered in the differential diagnosis of eyelid lesions resembling xanthelasma.
- Biopsy is crucial for accurate diagnosis.
- CO2 laser and surgical excision are effective treatment options with good prognosis.
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