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Related Experiment Video

Updated: Jun 21, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Chordoma in paranasal sinuses.

Reza Tabrizi¹, Mohammed Rakee, Birkan Taha Ozkan

¹Department of Oral and Maxillofacial Surgery, Craniomaxillofacial Surgery Research Center, University of Shiraz Medical Science, Shiraz, Iran. Tabmed@gmail.com

The Journal of Craniofacial Surgery

|July 24, 2009

Summary

Chordoma, a rare cranial base tumor, was treated in a 44-year-old man using surgery and radiotherapy. This aggressive approach led to no recurrence after one year, suggesting its efficacy.

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Surgical Treatment of an Endolymphatic Sac Tumor

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Area of Science:

Neurosurgery
Oncology
Radiotherapy

Background:

Chordoma is a rare, malignant intracranial tumor.
Cranial base chordomas typically present as extradural lesions.

Observation:

A case study of a 44-year-old male patient with chordoma involving the cranial base and paranasal sinuses.
The patient underwent a treatment regimen combining surgical intervention and radiotherapy.

Findings:

Surgical management included anterior cranial base osteotomy, lesion excision, and osteotomy segment reconstruction.
Postoperative radiotherapy was administered following surgical treatment.
One-year follow-up revealed no evidence of tumor recurrence.

Implications:

Aggressive surgical resection combined with postoperative radiotherapy appears to be a suitable treatment strategy for cranial base chordoma.
This multimodal approach may improve outcomes and reduce recurrence rates for this rare malignancy.