Related Experiment Video
Updated: Jun 21, 2026

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
Published on: May 30, 2011
[Magnetic resonance imaging of pulmonary perfusion. Technical requirements and diagnostic impact]
U I Attenberger1, M Ingrisch, K Büsing
1Institut für Klinische Radiologie und Nuklearmedizin, Universitätsmedizin Mannheim, Klinikum Mannheim der Universität Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim. ulrike.attenberger@medma.uni-heidelberg.de
Abstract:
With technical improvements in gradient hardware and the implementation of innovative k-space sampling techniques, such as parallel imaging, the feasibility of pulmonary perfusion MRI could be demonstrated in several studies. Dynamic contrast-enhanced 3D gradient echo sequences as used for time-resolved MR angiography have been established as the preferred pulse sequences for lung perfusion MRI. With these techniques perfusion of the entire lung can be visualized with a sufficiently high temporal and spatial resolution. In several trials in patients with acute pulmonary embolism, pulmonary hypertension and airway diseases, the clinical benefit and good correlation with perfusion scintigraphy have been demonstrated. The following review article describes the technical prerequisites, current post-processing techniques and the clinical indications for MR pulmonary perfusion imaging using MRI.
Insights
Pulmonary perfusion MRI is now feasible thanks to technical advances. This technique visualizes lung perfusion with high resolution, showing clinical benefit in various lung diseases.
Area of Science:
- Radiology and Imaging Science
- Cardiovascular and Respiratory Systems Imaging
- Medical Physics in MRI
Context:
- Advancements in gradient hardware and k-space sampling (e.g., parallel imaging) enhance MRI capabilities.
- Dynamic contrast-enhanced 3D gradient echo sequences are established for lung perfusion MRI.
- High temporal and spatial resolution allows comprehensive visualization of lung perfusion.
Purpose:
- To review the technical prerequisites for MR pulmonary perfusion imaging.
- To discuss current post-processing techniques for lung perfusion MRI.
- To outline clinical indications for MR pulmonary perfusion imaging.
Summary:
- Pulmonary perfusion MRI feasibility is demonstrated through technical improvements and innovative sampling techniques.
- Dynamic contrast-enhanced 3D gradient echo sequences are preferred for high-resolution lung perfusion visualization.
- Clinical trials show benefits in pulmonary embolism, hypertension, and airway diseases, correlating well with scintigraphy.
Impact:
- Enables detailed visualization of lung perfusion, aiding in diagnosis and management.
- Demonstrates clinical utility and correlation with established imaging modalities.
- Provides a comprehensive overview for clinicians and researchers in MR pulmonary perfusion imaging.
Related Concept Videos
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Magnetic Resonance Imaging
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies for Cardiovascular System IV: CMRI
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

