Related Experiment Video
Updated: Jun 21, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
[Cognitive effects of opioids]
1Cliniques universitaires Saint-Luc, Centre de référence multidisciplinaire de la douleur chronique, Bruxelles. Jacques.Grisart@uclouvain.be
Abstract:
This article discusses the potentially deleterious influence of opioids on cognitive functioning in chronic pain patients. Under stable doses of opioids, cognitive performances in patients are not inferior to those observed in healthy controls. During initialisation and/or adaptation of opioid treatment, a transient inferiority of cognitive performances is observed in chronic pain patients. Studies on combined effects of opioids and psychotropics on cognition are scarce. It is emphasized that cognitive dysfunction in chronic pain patients might be due to the attentional cost due to daily pain. Pain reduction by opioids may diminish this cost. Recommendations for driving under opioids are proposed.
More Related Videos
07:23Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
Published on: July 29, 2014
09:54Combining Laser Capture Microdissection and Microfluidic qPCR to Analyze Transcriptional Profiles of Single Cells: A Systems Biology Approach to Opioid Dependence
Published on: March 8, 2020
Related Concept Videos
Opioid Analgesics: Morphine and Other Natural Cogeners
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Analgesia and Pain Management
Opioid Receptors: Overview
Depressants
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...