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Exploiting the natural history of cytomegalovirus to vaccinate against HIV

Ellen E Sparger1, Murray B Gardner, Peter A Barry

  • 1Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. eesparger@ucdavis.edu

Expert Review of Vaccines
|July 25, 2009
PubMed
Abstract

No abstract available in PubMed .

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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...

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