Comparison of acute electrocardiographic presentation in patients with diastolic vs systolic heart failure
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Updated: Jun 21, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models
Published on: July 21, 2023
Karolina M Zareba1, Heather J Shenkman, John D Bisognano
1University of Rochester Medical Center, Rochester, NY, USA.
Abstract:
There are limited data comparing admission electrocardiograms (ECGs) in patients with acute diastolic (DHF) vs systolic heart failure (SHF) and their ability to predict cardiac events (CEs). Admission ECGs were evaluated in 241 acute heart failure patients (88 DHF; 153 SHF). DHF was defined as left ventricular ejection fraction >45%. End points consisted of rehospitalization for CEs or death during a 30-day follow-up. DHF patients had more atrial fibrillation (AF) while SHF patients had faster heart rates and longer QRS and QTc duration. There were 68 CEs: 26 (30%) in DHF and 42 (27%) in SHF patients ( P=.728). Multivariate logistic regression analysis revealed that in DHF patients, CEs were associated with nonischemic heart failure, blood urea nitrogen >28 mg/dL, and AF. In the SHF group, CEs were associated with AF. Admission ECG differs between acute DHF and SHF patients. CE rates are similar in both groups; AF is the only ECG parameter predictive of CEs.
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