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Updated: Jun 21, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Secondary hypopituitarism due to hypothalamic metastasis from small cell lung cancer]
Eva María Guerra Alía1, Pilar Garrido López, Vanesa Pachón Olmos
1Servicio de Oncología Médica. Hospital Universitario Ramón y Cajal. Madrid. España. eva_m_guerra@hotmail.com
Abstract:
Parasellar and hypothalamic metastases are uncommon. Their principal clinical manifestation is diabetes insipidus. Associated hypopituitarism is very rare. We report the case of a 54-year-old man with small cell lung cancer and hypopituitarism. A brain magnetic resonance imaging scan revealed a mass in the anterior region of the third ventricle with no clear etiology. The patient began chemotherapy treatment and the mass disappeared, which confirmed the diagnosis of secondary hypopituitarism caused by hypothalamic metastasis from small cell lung cancer.
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