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Published on: August 16, 2018
Sesquiterpenoids from Lactuca tatarica.
Xiao-Xiong Wang1, Xue Gao, Zhong-Jian Jia
1State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China.
Fitoterapia
|July 25, 2009
Summary
Researchers isolated two novel sesquiterpenoids, a guaianolide and an eudesmanolide, from Lactuca tatarica. Eight known sesquiterpenoids were also identified, expanding the known chemical constituents of this plant species.
Area of Science:
- Phytochemistry
- Natural Products Chemistry
- Organic Chemistry
Background:
- Lactuca tatarica is a plant species with potential medicinal properties.
- Sesquiterpenoids are a diverse class of natural products known for various biological activities.
Purpose of the Study:
- To isolate and characterize novel chemical compounds from Lactuca tatarica.
- To identify known sesquiterpenoids present in the plant.
Main Methods:
- Isolation of compounds using chromatographic techniques.
- Structure elucidation using Infrared (IR) spectroscopy, High-Resolution Electrospray Ionization Mass Spectrometry (HRESIMS), and 1D and 2D Nuclear Magnetic Resonance (NMR) spectroscopy.
- Identification of known compounds by comparing physical data with literature values.
Main Results:
- Isolation of one new guaianolide.
- Isolation of one new eudesmanolide.
- Identification of eight known sesquiterpenoids.
Conclusions:
- Lactuca tatarica is a source of structurally diverse sesquiterpenoids, including novel compounds.
- The identified compounds contribute to the understanding of the phytochemical profile of Lactuca tatarica.
