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Related Experiment Video

Updated: Jun 21, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Are we overpathologising motherhood?

Stephen Matthey1

  • 1University of Sydney, Sydney South West Area Health Service, Australia.

Journal of Affective Disorders
|July 25, 2009
PubMed
Summary

Maternal mental health screening may overestimate distress. Current methods, like the Edinburgh Depression Scale, can misidentify up to 50% of women as depressed. Re-evaluating risk factors and diagnostic criteria is crucial for accurate assessment.

Area of Science:

  • Perinatal mental health
  • Psychiatric epidemiology
  • Clinical psychology

Background:

  • Maternal psychiatric disorder rates are often based on self-report mood measures like the Edinburgh Depression Scale.
  • Screening for current or future distress also relies on these measures and psychosocial questions.

Purpose of the Study:

  • To critically evaluate the accuracy of current prevalence rates for maternal psychiatric disorders.
  • To examine the properties of the Edinburgh Scale and diagnostic criteria validity.
  • To assess the overestimation of women classified as 'at-risk'.

Main Methods:

  • Critical analysis of the Edinburgh Depression Scale's properties.
  • Examination of diagnostic criteria validity for perinatal populations.

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  • Evaluation of 'at-risk' classification based on single risk factors.

    • Main Results:

    • Approximately 50% of women scoring high on the Edinburgh Scale are not clinically depressed.
    • Revised, more conservative prevalence estimates are proposed.
    • Using repeat testing and correct cut-off scores can reduce overpathologizing.
    • Classifying women as 'at-risk' based on a single factor is questionable due to high prevalence of risk factors and low conversion to depression.

    Conclusions:

    • Current estimates of perinatal distress and at-risk status are likely overestimated.
    • Overpathologizing can occur through single high scores or single risk factors.
    • Improved assessment procedures are needed for accurate targeting of mental health interventions.