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An Optical Assay for Synaptic Vesicle Recycling in Cultured Neurons Overexpressing Presynaptic Proteins
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Postsynaptic Neuroligin1 regulates presynaptic maturation

Nina Wittenmayer1, Christoph Körber, Huisheng Liu

  • 1Institute for Anatomy and Cell Biology, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 307, D-69120 Heidelberg, Germany.

Proceedings of the National Academy of Sciences of the United States of America
|July 25, 2009
PubMed
Summary

The postsynaptic molecule Neuroligin1 is crucial for presynaptic terminal maturation. Neuroligin1 promotes synaptic vesicle recycling and active zone stability, essential for mature neuronal connections.

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