Can the ABCD2 risk score predict positive diagnostic testing for emergency department patients admitted for transient

Jon W Schrock1, Aaron Victor, Theodore Losey

  • 1Department of Emergency Medicine, MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44109-1998, USA. jschrock@metrohealth.org

Stroke
|July 25, 2009
PubMed

Insights

The ABCD2 score, used for transient ischemic attack risk, did not predict positive diagnostic tests in most evaluations. An elevated score may indicate severe carotid disease but is not recommended for guiding acute TIA diagnostic testing.

Area of Science:

  • Neurology
  • Diagnostic Imaging
  • Clinical Risk Stratification

Background:

  • Transient ischemic attack (TIA) evaluations require accurate risk stratification.
  • The ABCD2 score is a common tool for assessing TIA risk.
  • The utility of the ABCD2 score in predicting positive diagnostic test results is not well-established.

Purpose of the Study:

  • To determine if the ABCD2 score can predict positive diagnostic test results in patients acutely evaluated for TIA.
  • To assess the correlation between elevated ABCD2 scores and findings on various diagnostic tests.

Main Methods:

  • Retrospective cohort study of 256 patients with neurologist-confirmed TIA.
  • ABCD2 scores were calculated; patients with a score >= 4 were classified as high-risk.
  • Evaluated diagnostic tests included ECG, CT, MRI, MR angiography, carotid ultrasonography, and echocardiography.

Main Results:

  • 63% of patients had an elevated ABCD2 score (>= 4).
  • Diagnostic test completion rates varied significantly by modality.
  • An elevated ABCD2 score was significantly associated only with positive carotid duplex testing (P<0.05).

Conclusions:

  • An elevated ABCD2 score may predict severe carotid occlusive disease.
  • The ABCD2 score does not predict positive outcomes on other commonly ordered TIA diagnostic tests.
  • The ABCD2 score is not recommended for guiding diagnostic testing in acute TIA evaluations.
Abstract

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...