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Updated: Aug 18, 2026

Surgical Models of Gastroesophageal Reflux with Mice
Published on: August 25, 2015
[Prevention of postoperative reflux esophagitis in patients with duodenal ulcer]
Abstract:
The incidence of reflux-esophagitis was studied in 574 dispensary patients and 217 patients operated upon for ulcer disease. It was found that reflux-esophagitis is observed in 19.8% of patients with ulcer disease and in 34% of such patients subject to operation. The main cause of it is incompetence of the cardiac sphincter without or in combination with a hernia of the esophageal opening. It was noted that vagotomy leads to a disturbance of the ligamentous system of the cardio-esophageal zone and in all cases leads to the development of reflux-esophagitis. Fundoesophagorraphy is thought to be the best method of preoperative treatment of reflux-esophagitis.
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