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HPLC analysis of HEMA released from two different adhesive systems
Subutay Han Altintas1, Aslihan Usumez2
1Department of Prosthodontics, Karadeniz Technical University, Trabzon, Turkey.
Summary
This study found that the Optibond Solo Plus adhesive system released significantly more 2-Hydroxyethyl methacrylate (HEMA) than Single Bond over 21 days. Elution levels increased with time, highlighting the importance of adhesive choice in dental restorations.
Area of Science:
- Dental Materials Science
- Polymer Chemistry
- Biomaterials
Background:
- 2-Hydroxyethyl methacrylate (HEMA) is a common monomer in dental adhesives.
- Concerns exist regarding potential HEMA elution from resin-based dental materials.
- Understanding elution kinetics is crucial for assessing biocompatibility and long-term stability of dental restorations.
Purpose of the Study:
- To quantitatively assess in vitro HEMA elution from two distinct adhesive systems used with dual-cure resin cements.
- To compare HEMA elution profiles between Single Bond and Optibond Solo Plus adhesives.
- To determine the influence of time on HEMA elution from these adhesive systems.
Main Methods:
- High-performance liquid chromatography (HPLC) was employed to measure HEMA concentrations.
- Ceramic inlays were bonded to standardized Class I preparations using two resin cements with different adhesive systems.
- Specimens were immersed in 75% ethanol, and elution was measured at multiple time points up to 21 days.
Main Results:
- Statistically significant differences in HEMA elution were observed between the two adhesive systems (p < 0.01).
- Optibond Solo Plus demonstrated significantly higher HEMA elution compared to Single Bond (p < 0.01).
- HEMA elution increased significantly over the 21-day observation period (p < 0.01).
Conclusions:
- The choice of adhesive system significantly impacts HEMA elution, with Optibond Solo Plus releasing higher amounts.
- Time is a critical factor influencing the elution of HEMA from dental adhesive systems.
- These findings have implications for the selection of dental adhesives to minimize monomer release.
