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Cercarial Transformation and in vitro Cultivation of Schistosoma mansoni Schistosomules
Published on: August 16, 2011
The Schistosomiasis Control Initiative (SCI): rationale, development and implementation from 2002-2008.
A Fenwick1, J P Webster, E Bosque-Oliva
1Schistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, Imperial College, St. Mary's Campus, Norfolk Place, London W2 1PG, UK. a.fenwick@imperial.ac.uk
Parasitology
|July 28, 2009
Summary
Schistosomiasis control programs effectively reduced disease burden in Africa. Preventive chemotherapy strategies show promise for widespread implementation, though further funding is crucial for neglected tropical diseases (NTDs).
Area of Science:
- Tropical medicine
- Infectious diseases
- Public health
Background:
- Schistosomiasis is a major parasitic disease in developing nations, causing significant morbidity and economic impact.
- Despite increased focus, schistosomiasis control efforts in Africa face substantial funding gaps, receiving less than 20% of required resources.
Purpose of the Study:
- To evaluate the rationale, development, and objectives of Schistosomiasis Control Initiative (SCI)-supported programs.
- To assess management approaches, mapping, monitoring, evaluation, and impact of control initiatives.
- To examine drug resistance monitoring and national exit strategies for schistosomiasis control.
Main Methods:
- Review of SCI-supported schistosomiasis control programs across various countries.
- Analysis of management strategies, implementation approaches, and country-specific activities.
- Evaluation of mapping, monitoring, and impact assessment methodologies, including drug resistance surveillance.
Main Results:
- SCI-supported programs have successfully reduced morbidity associated with schistosomiasis.
- National programs utilizing preventive chemotherapy have demonstrated successful implementation in sub-Saharan Africa.
- Research by SCI strengthens the evidence base for effective schistosomiasis control.
Conclusions:
- Schistosomiasis control programs are effective in reducing disease burden.
- Preventive chemotherapy is a viable strategy for national schistosomiasis control programs in sub-Saharan Africa.
- Continued funding and integrated approaches are essential for expanding neglected tropical disease (NTD) control.
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