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Updated: Jun 21, 2026

A Comprehensive Protocol for Manual Segmentation of the Medial Temporal Lobe Structures
Published on: July 2, 2014
The anterior temporal lobes and the functional architecture of semantic memory
1Laboratory of Brain & Cognition, National Institute of Mental Health, Bethesda, Maryland 20892-1366, USA. simmonswkyle@mail.nih.gov
Abstract:
Recently, three accounts have emerged on the role of the anterior temporal lobes (ATLs) in semantic memory. One account claims that the ATLs are domain-general semantic hubs, another claims that they underlie knowledge of unique entities specifically, and yet another account claims that they support social conceptual knowledge generally. Here, we review neuropsychological and neuroimaging studies that bear on these three accounts and offer suggestions for future research to elucidate the roles of the ATLs in semantic memory.
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