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Updated: Jun 21, 2026

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Optical quality of foldable monofocal intraocular lenses before and after injection: comparative evaluation using a
Meritxell Vilaseca1, Montserrat Arjona, Jaume Pujol
1Center for Sensors, Instruments and Systems Development, Universitat Politècnica de Catalunya, Terrassa, Argentina. mvilasec@oo.upc.edu
Purpose:
To use the double-pass technique to evaluate the in vitro optical quality of foldable monofocal intraocular lenses (IOLs) used to correct aphakia.
Setting:
Universitat Politècnica de Catalunya, Terrassa, and Instituto de Microcirugía Ocular de Barcelona, Barcelona, Spain; Universidad Nacional de Tucumán, Tucumán, Argentina.
Methods:
This study assessed the in vitro optical quality of 7 IOLs before and after injection in an artificial eye that was attached to a double-pass system (Optical Quality Analysis System [OQAS]). The procedure imitated the conventional in vivo technique used to assess the optical quality of eyes with an IOL. The following parameters were evaluated: point-spread function, modulation transfer function (MTF), MTF cutoff frequency, Strehl ratio, and OQAS values.
Results:
The in vitro optical quality of most IOLs was as good after injection as before injection. In 1 IOL, the post-injection optical quality was statistically significantly different but the optical quality remained high.
Conclusions:
Results indicate that after an IOL is placed in the eye, its optical performance will be good, providing good visual quality. The eye cell model attached to the double-pass system was useful and effective for fully characterizing the optical quality of IOLs and evaluating variations resulting from the injection process.
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