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Related Experiment Video

Updated: Jun 21, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
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Desmoplastic ameloblastoma - A review.

Zhi-Jun Sun1, Yan-Ru Wu, Ning Cheng

  • 1Department of Oral and Maxillofacial Surgery, Wuhan University, Hubei, China. zhijundejia@yahoo.com.cn

Oral Oncology
|July 28, 2009
PubMed
Summary

Desmoplastic ameloblastoma (DA) is a rare tumor with distinct clinicoradiographic and histologic features. Resection significantly reduces recurrence rates compared to enucleation, highlighting its importance in managing this rare ameloblastoma variant.

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Area of Science:

  • Oral Pathology
  • Oncology
  • Radiology

Background:

  • Desmoplastic ameloblastoma (DA) is a rare variant of ameloblastoma.
  • DA exhibits unique clinical, imaging, and histological characteristics.
  • Understanding these features is crucial for accurate diagnosis and treatment planning.

Purpose of the Study:

  • To retrospectively analyze the clinicoradiographic features of desmoplastic ameloblastoma.
  • To compare treatment outcomes, specifically recurrence rates, based on surgical approach.
  • To highlight the distinctiveness of DA compared to conventional ameloblastomas.

Main Methods:

  • Retrospective analysis of 115 desmoplastic ameloblastoma cases from literature (1984-2008).
  • Review of clinical presentation, radiographic findings, and histological characteristics.

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  • Comparison of recurrence rates following enucleation versus resection.
  • Main Results:

    • DA affects males and females equally, predominantly in the 4th and 5th decades.
    • Commonly presents as a painless buccal swelling, often multilocular and ill-defined radiographically.
    • Resection yielded a 3.1% recurrence rate, significantly lower than enucleation's 21.1%.

    Conclusions:

    • Desmoplastic ameloblastoma presents with distinct clinicoradiographic and histological features.
    • Surgical resection is a more effective treatment modality for DA, minimizing recurrence.
    • DA represents a unique entity within the ameloblastoma spectrum.