Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 21, 2026

Intraoperative Ultrasound in Spinal Surgery

Intraoperative Ultrasound in Spinal Surgery

Published on: August 17, 2022

Spinal and paraspinal Ewing tumors.

Daniel J Indelicato¹, Sameer R Keole, Amir H Shahlaee

¹Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL 32206, USA. dindelicato@floridaproton.org

International Journal of Radiation Oncology, Biology, Physics

|July 28, 2009

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A modified Delphi consensus on tenosynovial giant cell tumour and giant cell tumour of bone : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM).

The bone & joint journal·2026

Same author

Ten-year outcomes for image-guided moderately hypofractionated proton therapy for prostate cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026

Same author

Long-Term Outcomes of Consolidative Proton Therapy for Pediatric Classical Hodgkin Lymphoma.

International journal of particle therapy·2026

Same author

Pulmonary Metastasectomy Versus Stereotactic Beam Radiation Therapy for Sarcoma Pulmonary Metastasis: A Retrospective Cohort Study.

Cureus·2025

Same author

A Systematic Study on Local Failure Events Post Chemoradiation Therapy for Cervical Cancer: Understanding the Impact of Baseline Lateral Anatomic Compartment Involvement.

International journal of radiation oncology, biology, physics·2025

Same author

Pattern of recurrence with 1.0 cm CTV in brain glioblastoma treated with radiotherapy.

Journal of neuro-oncology·2025

Aggressive treatment of spinal Ewing tumors with radiotherapy and surgery offers excellent local control and good neurologic recovery, despite significant toxicity. Further research should refine combined modality therapies and radiotherapy techniques.

Area of Science:

Oncology
Orthopedic Oncology
Radiation Oncology

Background:

Spinal and paraspinal Ewing tumors are rare but aggressive malignancies.
Optimal treatment strategies require long-term data analysis.

Purpose of the Study:

To review the University of Florida's 40-year experience treating spinal and paraspinal Ewing tumors.
To evaluate treatment outcomes, including survival, local control, and neurologic recovery.

Main Methods:

Retrospective review of 27 patients treated between 1965 and 2007.
Analysis of treatment modalities: radiotherapy (RT) alone versus surgery plus RT.
Evaluation of patient demographics, tumor characteristics, and treatment toxicities.

Main Results:

More Related Videos

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

Related Experiment Videos

Last Updated: Jun 21, 2026

Intraoperative Ultrasound in Spinal Surgery

Intraoperative Ultrasound in Spinal Surgery

Published on: August 17, 2022

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

5-year overall survival was 62%, with 71% for nonmetastatic disease.
Local control rates were 90% overall, and 89% for nonmetastatic disease.
Surgery plus RT yielded 100% local control; 7 of 9 patients with significant neurologic deficits recovered.

Conclusions:

Aggressive management with RT, with or without surgery, achieves high local control and good neurologic outcomes for spinal Ewing tumors.
High toxicity is associated with aggressive treatment, necessitating careful patient selection.
Future efforts should focus on optimizing combined modality treatments and advancing RT techniques.