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Poliovirus-mediated entry of pokeweed antiviral protein
T Lee1, M Crowell, M H Shearer
1Department of Biology, Southwest Texas State University, San Marcos 78666.
Antimicrobial Agents and Chemotherapy
|October 1, 1990
Abstract:
Infection of HeLa cells with poliovirus results in cell permeabilization to pokeweed antiviral protein. Cell permeabilization was dependent on the integrity of virus capsid proteins and directly proportional to the multiplicity of infection. This study demonstrates that virus adsorption is sufficient for the entry of pokeweed antiviral protein into poliovirus-infected cells.