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Updated: Dec 22, 2025

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
[Genetic aspects of smoking and impact on clinical care]
M Dobrinas1, J Cornuz, M Kohler Serra
1Center des Neurosciences Psychiatriques, Départment de Psychiatrie, CHUV, Université de Lausanne, Hôpital de Cery.
Abstract:
Tobacco smoking is a major public health issue and a better understanding of tobacco addiction represents an important challenge. Many factors are involved in tobacco addiction, including genetic factors. Taking them into account in smoking cessation programs would allow to better adapt these programs to individual characteristics and improve their rate of success. Given enzymatic induction by tobacco smoke, smoking cessation can nevertheless have important consequences on the metabolism of some drugs, that have to be taken into consideration. Here we present different clinical and genetic aspects of smoking and of smoking cessation. A dose adjustment of drugs influenced by tobacco smoke is proposed when quitting smoking.
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