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[Determination of total PSA rate and Gleason score during prostatic cancer in Urologic Hospital Center]
1Service d'Urologie-Andrologie du Centre Hospitalier Universitaire Aristide Le Dantec, Dakar, Sénégal.
Aim:
To dress biologic and histopathologic aspects of the prostatic cancer in urologic hospital center about a set of digital transrectal guided biopsies.
Methodology:
It is a prospective study realized between January 2002 and March 2002 (26 months) studying patients with positive prostatic biopsy.
Results:
Seventy two cases of prostatic cancer were noticed. Mean age of these patients was 69,9 years (54-91 years). Mean rate Total PSA was 134,8 ng/ml (6-2500 ng/ml). Repartition according Gleason score has revealed that only 35% of tumors were well differentiated. The study of correlation between Total PSA rate and Gleason grade has revealed that up to 10 ng/ml Total PSA rate, only 33% of patients had a Gleason grade between 2 and 4 (well differentiated tumor).
Conclusion:
Actual biologic and histopathologic profile of prostatic cancer lays emphasis on later management.
