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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
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Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
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Clinical Applications of Epidermal Stem Cells01:19

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Related Experiment Video

Updated: Jun 21, 2026

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
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Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay

Published on: June 25, 2019

Update on pathological skin picking.

Jon E Grant1, Brian L Odlaug

  • 1Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA. grant045@umn.edu

Current Psychiatry Reports
|July 29, 2009
PubMed
Summary
This summary is machine-generated.

Pathological skin picking (PSP) is a common disorder causing skin damage. Research suggests impaired inhibitory control and highlights the need for better treatments for this condition.

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Area of Science:

  • Psychiatry
  • Neuroscience

Background:

  • Pathological skin picking (PSP) is a prevalent disorder affecting 2-5.4% of the population.
  • Currently classified as an impulse control disorder not otherwise specified.
  • PSP shares phenomenological and clinical similarities with obsessive-compulsive disorder (OCD) and other body-focused repetitive behaviors (BFRBs).

Observation:

  • Animal neuroimaging studies in related disorders like OCD and trichotillomania offer insights into PSP.
  • Cognitive testing reveals impaired inhibitory control in individuals with PSP.
  • Despite its prevalence, effective treatments for PSP remain limited.

Findings:

  • Impaired inhibitory control is a key cognitive feature in PSP.
  • Neuroimaging research in related disorders provides a basis for understanding PSP's neurobiology.
  • The classification of PSP may need re-evaluation due to its similarities with OCD and BFRBs.

Implications:

  • Findings may aid in the accurate characterization and diagnosis of PSP.
  • Understanding impaired inhibitory control can guide the development of targeted interventions.
  • Further exploration of pharmacotherapeutic and cognitive-behavioral treatments is crucial for managing PSP.