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Published on: July 4, 2017
Hydrophilic high-luminescent magnetic nanocomposites
Xiaogang You1, Rong He, Feng Gao
1Department of Bio-Nano Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro and Nano Science and Technology, Shanghai Jiaotong University, Shanghai 200030, People's Republic of China.
Abstract:
In this study, hydrophilic high-luminescent magnetic nanocomposites (LMNCs) composed of both fluorescent clusters (quantum dots, QDs) and magnetic nanoparticles were synthesized. The nanocomposites exhibited high luminescence and were easily separated in an external magnetic field. The LMNCs were capped with streptavidin (SA), and the SA on the surface of LMNC-SA composites was confirmed to be bioactive by competitive inhibition analytic methods. The fabricated LMNC-SA composites have potential application in biolabelling, bioseparation, immunoassay and pathogenic diagnosis.
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