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Related Experiment Video

Updated: Jun 21, 2026

Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position

Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position

Published on: August 17, 2017

Fracture prevention in men.

Piet Geusens¹, Philip Sambrook, Willem Lems

¹Department of Rheumatology, Maastricht University Medical Center, Maastricht, The Netherlands. piet.geusens@scarlet.be

Nature Reviews. Rheumatology

|July 29, 2009

Summary

This summary is machine-generated.

Men face a lower lifetime fracture risk (20%) than women (50%), leading to less research. Recent advances improve osteoporosis case finding and fracture prevention in men, with available treatments like bisphosphonates and teriparatide.

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Transverse Fracture of the Mouse Femur with Stabilizing Pin

Transverse Fracture of the Mouse Femur with Stabilizing Pin

Published on: December 29, 2021

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Last Updated: Jun 21, 2026

Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position

Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position

Published on: August 17, 2017

Transverse Fracture of the Mouse Femur with Stabilizing Pin

Transverse Fracture of the Mouse Femur with Stabilizing Pin

Published on: December 29, 2021

Area of Science:

Gerontology
Orthopedics
Endocrinology

Background:

Men have a significantly lower lifetime fracture risk (20%) compared to women (50%).
Historically, less research has focused on male osteoporosis and fracture risk due to this disparity.
Differences in bone and fall-related factors contribute to sex-based variations in fracture incidence.

Purpose of the Study:

To review progress in identifying and preventing fractures in men.
To highlight advancements in understanding male osteoporosis pathophysiology.
To discuss current risk assessment tools and treatment options for male osteoporosis.

Main Methods:

Review of epidemiological studies on fracture prevalence and incidence in men.
Analysis of advancements in the pathophysiology of osteoporosis in men.
Evaluation of the FRAX algorithm for fracture risk assessment.
Assessment of available treatment options for male osteoporosis.

Main Results:

Epidemiology studies have refined understanding of fracture prevalence and incidence in men.
The FRAX algorithm enables personalized 10-year fracture risk calculation for both sexes.
Bisphosphonates show efficacy in improving bone mineral density and reducing vertebral fractures in men.
Teriparatide is a potential anabolic treatment for severe osteoporosis in men.

Conclusions:

Significant progress has been made in male osteoporosis research, particularly in case finding and prevention.
Risk assessment tools like FRAX are crucial for identifying high-risk individuals.
Effective pharmacological interventions, including bisphosphonates and teriparatide, are available for managing male osteoporosis.