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Published on: May 20, 2020
Antibiotics in food: legislation and validation of analytical methodologies
R Companyó1, M Granados, J Guiteras
1Departament de Química Analítica, Facultat de Química, Universitat de Barcelona, c/Martí i Franquès 1-11, 08028, Barcelona, Spain. compano@ub.edu
Abstract:
In this paper, European food safety legislation is presented, and special attention is devoted to monitoring residues of veterinary drugs in foodstuffs of animal origin. After a short review of the state of the art of analytical methodology for antibiotic residue analysis, the paper focuses on validation of analytical methods, with Decision 657/2002/EC as reference document. Finally, the main issues of the quality control of the analytical data, i.e. analysis of reference materials and participation in proficiency tests, are briefly addressed.
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Data Validation
Key parameters for method validation include:
Automated Microbial Diagnostics
Sources of Food Contamination
Biological Methods for Microbial Control
Methods for Controlling Microbial Growth
Clinical Significance of Antibiotic Resistance