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Updated: Jun 21, 2026

Measuring Nucleotide Binding to Intact, Functional Membrane Proteins in Real Time
Published on: March 11, 2021
NMR assignment of PN2-3, a tubulin interaction subdomain of the CPAP protein
Marie-Jeanne Clément1, Philippe Savarin, Jérôme Coutant
1Laboratoire Structure-Activité des Biomolécules Normales et Pathologiques, INSERM/UEVE U829-Université Evry-Val d'Essonne, Bâtiment Maupertuis, 91025, Evry, France.
Abstract:
We report the NMR assignment of the PN2-3 subdomain of the CPAP protein. It has been previously shown that this motif interacts with tubulin, inhibits microtubule nucleation from the centrosome and depolymerizes taxol-stabilized microtubules.
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