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Letrozole as a booster therapy in growth hormone deficiency
K V S Hari Kumar1, Muthukrishnan Jayaraman, Abhyuday Verma
1Department of Endocrinology, Medwin Hospitals, Nampally, Hyderabad 500 001, AP, India. hariendo@rediffmail.com
Abstract:
A 13 year old boy presented to us with short stature. Evaluation revealed growth hormone (GH) deficiency. He was treated with GH replacement for 10 months and to further boost up the growth potential, an aromatase inhibitor Letrozole was added to GH therapy. After one year of combination therapy, patient had significant improvement in predicted adult height without a negative impact on pubertal progression.
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