Related Experiment Video
Updated: Jun 21, 2026
Semi-Automatic Graphical Tool for Measuring Coronary Artery Spatially Weighted Calcium Score from Gated Cardiac Computed Tomography Images
Published on: September 22, 2023
Accuracy of noninvasive coronary stenosis quantification of different commercially available dedicated software
Riksta Dikkers1, Tineke P Willems, Gonda J de Jonge
1Department of Radiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. r.dikkers@rad.umcg.nl
Purpose:
The purpose of this study was to investigate the noninvasive quantification of coronary artery stenosis using cardiac software packages and vessel phantoms with known stenosis severity.
Materials And Methods:
Four different sizes of vessel phantoms were filled with contrast agent and scanned on a 64-slice multidetector computed tomography. Diameter and area stenosis were evaluated by 2 observers blinded from the true measures using 5 different software packages. Measurements were compared with the true measure of the vessel phantoms. The absolute difference in stenosis measurements and intraobserver and interobserver variabilities were assessed.
Results:
All software packages show a trend toward larger differences for the smaller vessel phantoms. The absolute difference of the automatic measurements was significantly higher compared with that of the manual measurements in all 5 evaluated software packages for all vessel phantoms (P < 0.05).
Conclusion:
Manual stenosis measurements are significantly more accurate compared with automatic measurements, and therefore, manual adjustments are still essential for noninvasive assessment of coronary artery stenosis.
