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Updated: Jun 21, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
The efficacy of demineralized bone matrix and cancellous bone chips for maxillary sinus augmentation
David M Kim1, Marc L Nevins, Marcelo Camelo
1Division of Periodontology, Department of Oral Medicine, Infection and Immunity, Harvard Shcool of Dental Medicine, Boston, Massachusetts. dkim@hsdm.harvard.edu
Abstract:
Demineralized bone matrix and cancellous bone chips in a reverse-phase medium carrier (DynaBlast, Keystone Dental) were used to augment the maxillary sinuses in 8 patients requiring 10 sinus augmentations. Clinical reentry after 6 to 7 months (mean, 6.2 months) and computed tomographic scan evaluation at 5 months demonstrated new bone formation as well as sufficient radiopaque volume to place implants in all sites. Microcomputed tomographic evaluation and histomorphometric analysis of sinus core biopsies confirmed the formation of new bone and demonstrated three distinctive mineralization patterns that have been previously described. DynaBlast can be considered a viable alternative to the use of autogenous bone or other types of grafting materials.
