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Updated: Jun 21, 2026

Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
[Triterpenoids from leaves of Ilex cornuta]
Zhirong Yao1, Jun Li, Sixiang Zhou
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Objective:
To investigate the chemical constituents of Ilex cornuta.
Method:
The chemical constituents were isolated by column chromatographic methods. And the structures were identified by spectral data.
Result:
Seven compounds were isolated and identified as follows: 2alpha-hydroxy ursolic acid (1), arjunolic acid (2), 23-hydroxy ursolic acid (3), 27-0-p-(Z) -coumaroyl ursolic acid (4), 27-O-p-(E)-coumaroyl ursolic acid (5), asiatic acid (6).
Conclusion:
Compound 1, 2 were obtained from this genus for the first time and 3-6 from this plant for the first time.

