Risk factors and predictors for surgical site infection after hepatic resection
T Okabayashi1, I Nishimori, K Yamashita
1Department of Surgery, Kochi Medical School, Kochi, Japan. tokabaya@kochi-u.ac.jp
The Journal of Hospital Infection
|July 31, 2009
Summary
Strict postoperative glucose control after liver resection is crucial for preventing surgical site infections (SSI). Using an artificial pancreas for glycaemic management significantly reduces SSI risk and improves patient outcomes.
Area of Science:
- Hepatobiliary Surgery
- Surgical Intensive Care
- Metabolic Control
Background:
- Surgical site infection (SSI) is a significant complication following hepatectomy.
- Effective postoperative management, including glucose control, is vital for reducing patient morbidity and mortality.
Purpose of the Study:
- To identify risk factors and predictors for SSI after hepatic resection.
- To evaluate the impact of postoperative glucose control methods on SSI incidence.
Main Methods:
- A retrospective analysis of 152 patients undergoing hepatic resection.
- Multivariate analysis to identify independent predictors of SSI.
- Comparison of SSI rates between different glucose control strategies.
Main Results:
- The overall SSI incidence was 14.5%.
- Independent risk factors for SSI included higher body mass index, greater blood loss, and postoperative bile leakage.
- The sliding scale method for glucose control was associated with increased SSI risk, while the artificial pancreas showed no SSI cases.
Conclusions:
- Postoperative glycaemic control is a critical factor in preventing infectious complications after liver resection.
- Obesity, intraoperative blood loss, and bile leakage are significant risk factors for SSI.
- The artificial pancreas is a safe and effective tool for achieving strict glycaemic control, reducing SSI incidence in hepatectomised patients.

