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Grape consumption supports immunity in animals and humans
1Food Science and Human Nutrition, University of Florida, Gainesville, FL 32611, USA. percival@ufl.edu
Grapes and grape products may support immune function, particularly gammadelta T cells. Research suggests Concord grape juice specifically helps maintain these immune cells and overall immunity.
Area of Science:
- Nutritional immunology
- Plant bioactives and immune response
Background:
- Nutrients are essential for immune system function.
- Certain plant compounds may uniquely interact with gammadelta T cells.
- Proanthocyanidins and anthocyanins in plants are potential candidates.
Purpose of the Study:
- To investigate the hypothesis that grapes support immune response, specifically gammadelta T cells.
- To review existing literature on grape products and their immune interactions.
- To explore the potential of grapes in modulating gammadelta T cell activity.
Main Methods:
- Review of animal studies demonstrating immune support from grape products.
- Analysis of a human intervention study using Concord grape juice.
- Comparison of immune function markers in participants consuming grape juice versus placebo.
Main Results:
- Animal studies indicate grape products support immune function.
- A human study showed Concord grape juice supported circulating gammadelta T cells.
- Placebo group in the human study exhibited changes associated with reduced immunity.
Conclusions:
- Grapes and their products show potential in supporting immune health.
- Concord grape juice may play a role in maintaining gammadelta T cell populations.
- Further research is warranted to elucidate the mechanisms of grape-immune interactions.
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