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Updated: Jun 21, 2026

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Sperm Collection of Differential Quality Using Density Gradient Centrifugation
Published on: November 29, 2018
[Corelation between hyperviscosity of the ejaculate and physical-morphological and biochemical parameters]
L Bobák1, J Rosocha, L Lehocká
1Zdruieni tkanivová banka, Lekárska fakulta Univerzity P. J. Safárika a FN L. Pasteura, Kosice.
Ceska Gynekologie
|August 1, 2009
Summary
High semen viscosity is linked to reduced sperm motility and increased abnormalities, potentially indicating urogenital infections. This parameter is crucial for male fertility assessment.
Area of Science:
- Andrology
- Reproductive Medicine
- Urology
Context:
- Semen hyper-viscosity is a complex parameter in male fertility.
- Understanding its relationship with semen quality and infection is vital.
- Previous studies have explored various semen parameters, but the link between hyper-viscosity and specific biochemical and morphological factors, especially in the context of infection, requires further elucidation.
Purpose:
- To investigate the correlation between seminal hyper-viscosity and physical-morphological, biochemical ejaculate parameters.
- To explore the potential influence of local urogenital infections on semen viscosity and associated parameters.
- To assess the diagnostic value of hyper-viscosity in male fertility evaluations.
Summary:
- A retrospective analysis of 100 men with increased semen viscosity revealed significant correlations between hyper-viscosity, reduced sperm motility, and increased morphological abnormalities.
- Asthenozoospermia cases showed links between polymorphonuclear granulocytes (PMN), higher seminal fluid pH, decreased sperm vitality, reduced seminal plasma fructose, and positive microbiology.
- High visco-elasticity positively correlated with positive microbiology, even with low rates of leukocytospermia, suggesting latent infections.
Impact:
- Hyper-viscosity is a simple yet significant parameter for male fertility assessment, associated with asthenoteratozoospermia.
- Lowering leukocytospermia cutoff criteria may aid in detecting chronic or latent urogenital infections.
- The combination of viscopathy and asthenoteratozoospermia may serve as indicators for microbiological examination.
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