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Related Experiment Video

Updated: Jun 21, 2026

Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia

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Catatonia recognition and treatment.

Olivier Cottencin¹, Thierry Danel, Michel Goudemand

¹Department of Consultation Liaison Psychiatry, AP-HP European Georges Pompidou Hospital, University of Medicine, Paris, France. ocottencin@chru-lille.fr

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

|August 1, 2009

Summary

Catatonia can occur after alcohol withdrawal, even in patients with bipolar disorder. Zolpidem administration rapidly improved symptoms, suggesting its diagnostic and therapeutic utility.

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Area of Science:

Psychiatry
Neurology

Background:

Catatonia is increasingly linked to mood disorders and medical conditions, not solely schizophrenia.
Alcohol withdrawal is identified as a potential stressor contributing to catatonia.

Observation:

A 54-year-old woman with type II bipolar disorder developed catatonia 48 hours post-alcohol withdrawal.
She had also ceased other prescribed treatments prior to symptom onset.

Findings:

Catatonia can manifest as a nonspecific response to various stressors.
Alcohol withdrawal may represent an additional risk factor for developing catatonia.

Implications:

This case highlights alcohol withdrawal as a potential trigger for catatonia.
The zolpidem challenge test demonstrates value in diagnosing and treating catatonia.