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Updated: Jun 21, 2026
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TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
Published on: April 13, 2021
[Follow-up of the kidney donor]
Luciana Bonfante1, A Gemelli, A D'Angelo
1Clinica Nefrologica, Dipartimento di Scienze Mediche e Chirurgiche, Università degli Studi, Padova. luciana.bonfante@unipd.it
Summary
Living donor kidney transplants offer the best outcomes. However, long-term donor health risks, like chronic kidney disease and cardiovascular issues, require further study with extended follow-up.
Area of Science:
- Nephrology
- Transplant Surgery
- Public Health
Context:
- Living donor kidney transplantation is the optimal renal replacement therapy.
- While increasing in Italy, long-term donor safety data remains limited.
- Existing research often lacks sufficient follow-up duration and subject numbers.
Purpose:
- To investigate the long-term health risks for living kidney donors.
- To define the incidence and nature of chronic kidney disease (CKD) post-donation.
- To assess potential differences in nephropathy and cardiovascular risk compared to individuals with two kidneys.
Summary:
- Long-term complications for living kidney donors, including chronic kidney disease (CKD) and microalbuminuria, are not well-defined.
- The pathophysiology of GFR decline and proteinuria in donors may differ from patients with bilateral kidneys.
- Prolonged, detailed follow-up is essential for monitoring and managing potential donor complications.
Impact:
- Highlights the need for comprehensive, long-term monitoring of living kidney donors.
- Informs future research on donor health outcomes and risk stratification.
- Aids in optimizing post-donation care protocols to ensure donor well-being and mitigate long-term risks.
Related Concept Videos
01:28Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
01:26Kidney Transplant II: Surgical Procedure
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01:16Kidney Transplant III: Nursing Management
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01:45Kidney Structure
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
01:24Tissue Transplantation
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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The Biology of Tissue Transplantation
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01:22Bone Marrow Sampling and Transplants
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