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Kinetic Screening of Nuclease Activity using Nucleic Acid Probes
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Probing for actinase activity of protealysin

O A Tsaplina1, T N Efremova, L V Kever

  • 1Institute of Cytology, Russian Academy of Sciences, St. Petersburg, 194064, Russia.

Biochemistry. Biokhimiia
|August 4, 2009
PubMed
Summary

Protealysin, a bacterial metallopeptidase, cleaves actin and activates matrix metalloprotease MMP2. This actinase activity may facilitate bacterial invasion of eukaryotic cells, as observed with Serratia proteamaculans 94.

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