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Published on: August 22, 2025
Prognosis of idiopathic downbeat nystagmus
Judith Wagner1, Nadine Lehnen, Stefan Glasauer
1Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany. judith.wagner@med.uni-muenchen.de
Abstract:
Downbeat nystagmus (DBN) is a common form of acquired involuntary ocular oscillation overriding fixation. Little is known about the natural evolution of DBN in idiopathic cases. Therefore, eye movements were recorded in seven patients with idiopathic DBN by search-coil technique over a course of up to six years. Neither the slow-phase velocity (SPV) nor the dependency of the SPV on gaze position as an indicator of dysfunction of the oculomotor velocity-to-position integrator changed significantly over the time course investigated in this study.
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