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Sleep duration and mortality: a systematic review and meta-analysis.
Lisa Gallicchio1, Bindu Kalesan
1The Prevention and Research Center, The Weinberg Center for Women's Health & Medicine, 227 St. Paul Place, 6th Floor, Baltimore, MD 21202, USA. Lgallic@mdmercy.com
Journal of Sleep Research
|August 4, 2009
Summary
Both short and long sleep durations are linked to increased all-cause mortality risk. This systematic review highlights the importance of sleep duration for overall health outcomes.
Area of Science:
- Epidemiology
- Sleep Medicine
- Public Health
Background:
- Epidemiologic studies suggest a link between sleep duration and overall mortality.
- Understanding the relationship between sleep patterns and mortality is crucial for public health.
Purpose of the Study:
- To systematically review and meta-analyze associations between sleep duration (short and long) and all-cause and cause-specific mortality in adults.
Main Methods:
- Systematic literature search of PubMed up to January 2008.
- Inclusion of 23 studies measuring sleep duration via self-report.
- Random-effects meta-analysis to pool relative risks (RRs) for mortality.
Main Results:
- Short sleep duration was associated with a 10% increased risk of all-cause mortality (RR: 1.10).
- Long sleep duration was associated with a 23% increased risk of all-cause mortality (RR: 1.23).
- Increased risks were also observed for cardiovascular-related and cancer-related mortality, particularly for long sleepers.
Conclusions:
- Both short and long sleep durations are associated with increased all-cause mortality risk.
- Findings suggest a non-linear relationship between sleep duration and mortality.
- Further research using objective sleep measures is recommended to confirm these associations.
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