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[Comparative analysis of genomes of oncogenic B-lymphotropic herpesviruses reproducing in cell lines obtained from
Biulleten' Eksperimental'Noi Biologii I Meditsiny
|December 1, 1990
Abstract:
The aim of this work was to study genomes of B-lymphotropic oncogenic herpesviruses of Macaca arctoides (HVMA), Papio hamadryas (HVP) and Cercopithecus aethiops (HVGM). Blot-hybridization detected inter- and intraspecific genome heterogeneity of investigated viruses in restriction sites EcoR1, Pst1 and Hind111. Virus-specific sequences in two-cell lines obtained from HVMA-induced rabbit tumours can prove HVMA a role in malignant tumour induction in rabbits.