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A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers
Published on: January 5, 2024
Pediatric fibromyalgia
1Division of Internal Medicine, Department of Medicine H, Soroka Medical Center, Ben Gurion University, Beer Sheva, Israel. dbuskila@bgu.ac.il
Insights
Fibromyalgia is a chronic pain condition affecting children and adolescents, characterized by widespread pain and fatigue. This review covers its causes, symptoms, and treatment in young people.
Area of Science:
- Pediatric Rheumatology
- Pain Medicine
- Clinical Neurology
Background:
- Fibromyalgia is a chronic pain disorder characterized by widespread musculoskeletal pain, fatigue, and sleep disturbances.
- Central nervous system sensitization is a key pathophysiological mechanism.
- While common in adults, pediatric fibromyalgia presents unique challenges.
Purpose of the Study:
- To provide a comprehensive review of pediatric fibromyalgia.
- To discuss the epidemiology, clinical presentation, and etiology of fibromyalgia in children and adolescents.
- To outline current management strategies and expected outcomes for pediatric fibromyalgia.
Main Methods:
- Literature review of epidemiological studies, clinical case series, and treatment trials.
- Synthesis of data on diagnostic criteria, symptom complexes, and risk factors.
- Analysis of treatment modalities and prognostic indicators.
Main Results:
- Pediatric fibromyalgia shares core features with adult fibromyalgia but may have distinct epidemiological patterns.
- Associated symptoms like fatigue, sleep issues, and cognitive difficulties are prominent.
- Multimodal treatment approaches are generally recommended.
Conclusions:
- Fibromyalgia can affect children and adolescents, impacting their quality of life.
- Early diagnosis and comprehensive management are crucial for optimal outcomes.
- Further research is needed to fully understand pediatric fibromyalgia's long-term trajectory.
Abstract:
Fibromyalgia is an idiopathic chronic pain syndrome defined by widespread nonarticular musculoskeletal pain and generalized tender points. The syndrome is associated with a constellation of symptoms, including fatigue, nonrefreshing sleep, irritable bowel, and more. Central nervous system sensitization is a major pathophysiologic aspect of fibromyalgia; in addition, various external stimuli such as trauma and stress may contribute to development of the syndrome. Fibromyalgia is most common in midlife, but may be seen at any age. This article reviews the epidemiology, clinical characteristics, etiology, management, and outcome of pediatric fibromyalgia.
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