Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
iPS Cell Differentiation01:22

iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Autonomy under uncertainty: the structural limits of substituted judgment in clinical practice.

Monash bioethics review·2026
Same author

Bolus-Tracked Biphasic Contrast-Enhanced CT Imaging Following Microwave Liver Ablation Improves Ablation Zone Conspicuity and Semi-automatic Segmentation Quality.

Cardiovascular and interventional radiology·2025
Same author

Tumor Suppressor miR-34a: Potential Biomarker of TACE Response in HCC.

Cardiovascular and interventional radiology·2024
Same author

Quantifying treatment burden: the patient burden score a study of 758 patients across three clinical urologic scenarios.

World journal of urology·2024
Same author

Interventional Oncology Meets Immuno-oncology: Combination Therapies for Hepatocellular Carcinoma.

Radiology·2024
Same author

Immune Modulation in Untreated, Contralateral Hepatic Metastases after Yttrium-90 Radioembolization of Microsatellite Stable Colorectal Cancer.

Journal of vascular and interventional radiology : JVIR·2024
Same journal

Reply to "Clarifying Recurrence, Bleeding Risk, and Procedural Burden in Central Renal Tumor Ablation".

Journal of vascular and interventional radiology : JVIR·2026
Same journal

Cryoablation of Abdominal Wall Endometriosis: Evidence Base Calling for Greater Awareness of this Minimally Invasive Option.

Journal of vascular and interventional radiology : JVIR·2026
Same journal

Specially Designed Double-Loop Versus Single-Loop 10.2-Fr Multihole Pigtail Catheters for Pleural Effusion Drainage: A Retrospective Comparative Study of Procedural Efficiency, Catheter Stability, and Safety.

Journal of vascular and interventional radiology : JVIR·2026
Same journal

CT-Based Intratumoral Artery-Like Volume for Pre-Treatment Lung Shunt Estimation in Hepatocellular Carcinoma.

Journal of vascular and interventional radiology : JVIR·2026
Same journal

Socioeconomic Factors Impacting Survival in Patients with Hepatocellular Carcinoma Treated with Locoregional Therapies: A Single-Center Study.

Journal of vascular and interventional radiology : JVIR·2026
Same journal

2026 SIR Dotter Lecturer of the Society of Interventional Radiology Interventional Radiology: A Journey of Creativity.

Journal of vascular and interventional radiology : JVIR·2026
See all related articles

Related Experiment Video

Updated: Jun 21, 2026

Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice
10:25

Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice

Published on: June 13, 2012

Stem cell therapy: a primer for interventionalists and imagers.

Boris Nikolic1, Salomao Faintuch, S Nahum Goldberg

  • 1Department of Radiology, Beth Israel Deaconess Medical Center-Harvard Medical School, One Deaconess Road, Boston, MA 02215, USA. boris.nikolic@uphs.upenn.edu

Journal of Vascular and Interventional Radiology : JVIR
|August 4, 2009
PubMed
Summary
This summary is machine-generated.

Diagnostic and interventional radiologists play a crucial role in advancing stem cell therapy. Their expertise in imaging, tracking, and targeted delivery enhances patient care for incurable diseases.

More Related Videos

Stem Cell Transplantation in an in vitro Simulated Ischemia/Reperfusion Model
09:15

Stem Cell Transplantation in an in vitro Simulated Ischemia/Reperfusion Model

Published on: November 5, 2011

Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds
09:18

Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds

Published on: July 16, 2018

Related Experiment Videos

Last Updated: Jun 21, 2026

Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice
10:25

Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice

Published on: June 13, 2012

Stem Cell Transplantation in an in vitro Simulated Ischemia/Reperfusion Model
09:15

Stem Cell Transplantation in an in vitro Simulated Ischemia/Reperfusion Model

Published on: November 5, 2011

Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds
09:18

Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds

Published on: July 16, 2018

Area of Science:

  • Regenerative Medicine
  • Radiology
  • Biomedical Engineering

Background:

  • Stem cell therapy research is advancing rapidly, generating significant clinical and public interest.
  • Potential applications include treating currently incurable diseases like Parkinson disease and diabetes mellitus.
  • Radiologists' involvement is vital for the successful bench-to-bedside translation of these therapies.

Purpose of the Study:

  • To highlight the essential roles of diagnostic and interventional radiologists in stem cell therapy development.
  • To emphasize the unique contributions of radiology to stem cell research and clinical application.

Main Methods:

  • Diagnostic radiologists can specialize in imaging, tracking, and monitoring stem cell engraftment.
  • Interventional radiologists are adept at targeted stem cell delivery via various routes (e.g., percutaneous, intravenous, intraarterial).
  • Interventionalists may also prepare the engraftment site through controlled tissue destruction (e.g., thermal ablation) to enhance stem cell integration.

Main Results:

  • Radiologists offer critical expertise in visualizing and quantifying stem cell behavior in vivo.
  • Targeted delivery techniques ensure precise stem cell placement, maximizing therapeutic potential.
  • Pre-conditioning of target tissues can improve the efficacy of stem cell transplantation.

Conclusions:

  • Active participation of radiologists in stem cell therapy research is essential for patient care.
  • Integrating radiological expertise accelerates the development and clinical application of stem cell treatments.
  • The combined skills of diagnostic and interventional radiology offer comprehensive support for stem cell therapy.