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Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...

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Related Experiment Video

Updated: Jun 21, 2026

Acupoint Catgut Embedding for Treatment of Chronic Pelvic Pain Due to the Sequelae of Pelvic Inflammatory Disease
02:41

Acupoint Catgut Embedding for Treatment of Chronic Pelvic Pain Due to the Sequelae of Pelvic Inflammatory Disease

Published on: May 3, 2024

Chronic pelvic pain.

Andrew Paul Baranowski1

  • 1The Centre for Urogenital Pain Medicine, University College London Hospitals Foundation Trust, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK. apbuk@btinternet.com

Best Practice & Research. Clinical Gastroenterology
|August 4, 2009
PubMed
Summary
This summary is machine-generated.

Chronic pelvic pain involves the central nervous system, leading to widespread symptoms beyond the initial trigger. Effective management requires a multidisciplinary approach, not just end-organ treatment.

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Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
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Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

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Demonstration of Cutaneous Allodynia in Association with Chronic Pelvic Pain
06:44

Demonstration of Cutaneous Allodynia in Association with Chronic Pelvic Pain

Published on: June 23, 2009

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Last Updated: Jun 21, 2026

Acupoint Catgut Embedding for Treatment of Chronic Pelvic Pain Due to the Sequelae of Pelvic Inflammatory Disease
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Published on: May 3, 2024

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
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Demonstration of Cutaneous Allodynia in Association with Chronic Pelvic Pain
06:44

Demonstration of Cutaneous Allodynia in Association with Chronic Pelvic Pain

Published on: June 23, 2009

Area of Science:

  • Neurology
  • Pain Medicine
  • Urology

Background:

  • Chronic pelvic pain (CPP) affects diverse populations, suggesting shared underlying mechanisms.
  • Central nervous system (CNS) involvement can transform localized pain into complex regional pain syndromes.
  • Predisposed individuals may develop sensory and functional abnormalities from seemingly minor triggers.

Purpose of the Study:

  • To elucidate the central nervous system's role in chronic pelvic pain syndromes.
  • To highlight the multifaceted nature of CPP, encompassing sensory, functional, and systemic aspects.
  • To emphasize the necessity of integrated management strategies for CPP.

Main Methods:

  • Review of existing literature on CPP mechanisms.
  • Analysis of CNS involvement in pain perception and modulation.
  • Examination of associated functional and systemic disorders.

Main Results:

  • CNS involvement can lead to heightened pain sensitivity and amplified sensations.
  • CPP is associated with visceral dysfunction, continence issues, and musculoskeletal disability.
  • Psychological, behavioral, sexual, and social factors are integral to the CPP experience.

Conclusions:

  • End-organ treatment alone is insufficient for CPP.
  • A comprehensive, interdisciplinary approach is crucial for managing chronic pelvic pain syndromes.
  • Understanding CNS mechanisms is key to developing effective CPP treatments.