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Intestinal intussusception in adults due to acute enterovirus infection

A Y Chia1, J K Chia

  • 1EV Med Research, Lomita, California 90717, USA.

Journal of Clinical Pathology
|August 4, 2009
PubMed

Insights

Three adult intussusception cases were linked to enteroviruses. A new mechanism involving tap water suggests improved water monitoring could prevent future non-polio enterovirus infections.

Area of Science:

  • Virology
  • Gastroenterology
  • Epidemiology

Background:

  • Intussusception is a rare condition in adults.
  • Enteroviruses are common viral pathogens.
  • Outbreaks of non-polio enterovirus infections can occur.

Observation:

  • Three adult intussusception cases occurred within three weeks.
  • Enterovirus RNA was detected in stool samples.
  • Enterovirus protein was identified in resected intestinal tissue.

Findings:

  • A novel mechanism linking enteroviruses to intussusception in adults is proposed.
  • Tap water was identified as a potential source in this outbreak.
  • Non-polio enterovirus infection is associated with adult intussusception.

Implications:

  • Enhanced drinking-water monitoring may prevent future non-polio enterovirus outbreaks.
  • Understanding the link between enteroviruses and intussusception can improve diagnosis and treatment.
  • This study highlights the importance of virological surveillance in unexplained gastrointestinal conditions.

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