Prognostic factors in jejuno-ileal atresia

Sathyaprasad C Burjonrappa1, Elise Crete, Sarah Bouchard

  • 1Department of Pediatric Surgery, New York Medical College, Valhalla, NY, USA. sathyabc@yahoo.com

Insights

Jejuno-ileal atresias (JIA) outcomes are good for mild cases, but severe JIA and associated anomalies increase mortality risk. Reintervention for adhesions is common in the first year.

Area of Science:

  • Pediatric Surgery
  • Neonatal Care
  • Gastrointestinal Surgery

Background:

  • Jejuno-ileal atresias (JIA) are congenital obstructions of the small intestine.
  • Outcomes and prognostic factors for JIA require further investigation.

Purpose of the Study:

  • To investigate morbidity and mortality in jejuno-ileal atresias (JIA).
  • To identify prognostic factors influencing JIA patient outcomes.
  • To determine the incidence of reintervention in JIA patients.

Main Methods:

  • Retrospective review of 63 patients diagnosed with JIA.
  • Data collected over a 30-year period (1975-2005).

Main Results:

  • 52% of JIA patients had associated anomalies.
  • Seven deaths occurred, with associated anomalies and severe atresia types (IV/V) being significant factors (P = 0.017 and P = 0.007, respectively).
  • Nine patients required reoperations for adhesions within the first year.

Conclusions:

  • Mild JIA cases demonstrate excellent prognosis and long-term survival.
  • Severe JIA is linked to prolonged parenteral nutrition and secondary procedures for intestinal failure.
  • Associated anomalies negatively impact outcomes in jejuno-ileal atresias.
Abstract

Related Concept Videos

Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...